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Mc-O-Si(di-iso)-Cl

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Catalog No. T18313

Mc-O-Si(di-iso)-Cl is a cleavable ADC linker, frequently used in the synthesis of antibody-drug conjugates (ADCs) such as Gemcitabine-O-Si(di-iso)-O-Mc [1].

Mc-O-Si(di-iso)-Cl

Mc-O-Si(di-iso)-Cl

😃Good
Catalog No. T18313
Mc-O-Si(di-iso)-Cl is a cleavable ADC linker, frequently used in the synthesis of antibody-drug conjugates (ADCs) such as Gemcitabine-O-Si(di-iso)-O-Mc [1].
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Product Introduction

Bioactivity
Description
Mc-O-Si(di-iso)-Cl is a cleavable ADC linker, frequently used in the synthesis of antibody-drug conjugates (ADCs) such as Gemcitabine-O-Si(di-iso)-O-Mc [1].
In vitro
Antibody-drug conjugates (ADCs) consist of an antibody linked to a cytotoxic drug via an ADC linker[1].
Chemical Properties
Molecular Weight331.91
FormulaC15H26ClNO3Si
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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Keywords

Mc-O-Si(di-iso)-ClMc O Si(di iso) ClMcOSi(diiso)Cl
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