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Methylene Violet 3RAX

🥰Excellent
Catalog No. T77235Cas No. 4569-86-2

Methylene Violet 3RAX is a cationic dye, a potential photosensitizer in photodynamic therapy, with antitumor activity that alters the molecular structure of DNA, disrupts the modules of DNA, and induces the production of reactive monoclinic oxygen species, which are used to stain the mitochondria of cells.Methylene Violet 3RAX inhibits the subcellular localization of cancer cells by severing the Methylene Violet 3RAX inhibits subcellular localization of cancer cells, leading to cell death by cutting DNA strands in tumor cells.

Methylene Violet 3RAX

Methylene Violet 3RAX

🥰Excellent
Catalog No. T77235Cas No. 4569-86-2
Methylene Violet 3RAX is a cationic dye, a potential photosensitizer in photodynamic therapy, with antitumor activity that alters the molecular structure of DNA, disrupts the modules of DNA, and induces the production of reactive monoclinic oxygen species, which are used to stain the mitochondria of cells.Methylene Violet 3RAX inhibits the subcellular localization of cancer cells by severing the Methylene Violet 3RAX inhibits subcellular localization of cancer cells, leading to cell death by cutting DNA strands in tumor cells.
Pack SizePriceAvailabilityQuantity
10 mg$32In Stock
25 mg$50In Stock
50 mg$72In Stock
100 mg$98In Stock
500 mg$256In Stock
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Product Introduction

Bioactivity
Description
Methylene Violet 3RAX is a cationic dye, a potential photosensitizer in photodynamic therapy, with antitumor activity that alters the molecular structure of DNA, disrupts the modules of DNA, and induces the production of reactive monoclinic oxygen species, which are used to stain the mitochondria of cells.Methylene Violet 3RAX inhibits the subcellular localization of cancer cells by severing the Methylene Violet 3RAX inhibits subcellular localization of cancer cells, leading to cell death by cutting DNA strands in tumor cells.
Targets&IC50
BChE (human plasma):0.51 μM (Ki), AChE (human erythrocyte):1.58 μM (Ki)
In vitro
Methylene Violet 3RAX was able to inhibit human erythrocyte AChE and human plasma BChE with Ki of 1.58 μM and 0.51 μM, respectively. [2] It also exhibited antitumor activity, which is achieved by cleaving DNA strands in tumor cells. Methylene Violet 3RAX significantly enhances DNA cleavage in the concentration range of 0-400 µM. At a concentration of 300 µM, its DNA photocleavage activity exceeded 60%. [1]
Chemical Properties
Molecular Weight378.9
FormulaC22H23ClN4
Cas No.4569-86-2
Smiles[Cl-].N=1C=2C=CC(N)=CC2[N+](C=3C=CC=CC3)=C4C=C(C=CC14)N(CC)CC
Storage & Solubility Information
Storagekeep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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