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Methyltetrazine-amido-PEG5-alkyne, a polyethylene glycol (PEG) derivative, is commonly employed as a linker in proteolysis targeting chimeras (PROTACs) synthesis [1].
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | 7-10 days | |
500 mg | Inquiry | 7-10 days |
Description | Methyltetrazine-amido-PEG5-alkyne, a polyethylene glycol (PEG) derivative, is commonly employed as a linker in proteolysis targeting chimeras (PROTACs) synthesis [1]. |
In vitro | PROTACs consist of two ligands connected by a linker: one binds to an E3 ubiquitin ligase, and the other targets a specific protein. They leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight | 487.55 |
Formula | C24H33N5O6 |
Cas No. | 2322322-23-4 |
Relative Density. | 1.181 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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