methyltetrazine amido peg5 alkyne

Methyltetrazine-amido-PEG5-alkyne, a polyethylene glycol (PEG) derivative, is commonly employed as a linker in proteolysis targeting chimeras (PROTACs) synthesis [1].

Thalidomide-O-amido-PEG-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate, incorporating a Thalidomide-based cereblon ligand and a linker. This compound is used in the synthesis of PROTACs.

Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2 is a synthetic conjugate that combines a Thalidomide-based cereblon ligand and a linker, commonly utilized in PROTAC technology. This compound serves as a connector between the target protein and the E3 ligase, facilitating targeted protein degradation.

Methyltetrazine-PEG5-NHS ester, a PEG-linked PROTAC linker, enables the synthesis of PROTACs[1].

Boc-N-Amido-PEG5-Ms is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Mal-amido-PEG10-C2-NHS ester is a noncleavable ADC linker with a maleimide group and an NHS ester, used as a labeling agent for primary amines (-NH2) in proteins, amine-modified oligonucleotides, and other amine-containing molecules [1][2].

Amino-PEG6-amido-bis-PEG5-N3 is a cleavable 11-unit polyethylene glycol (PEG) linker utilized in the synthesis of antibody-drug conjugates (ADCs) [1].

Thalidomide-O-amido-PEG-C2-NH2 is a synthesized conjugate formulation designed as an E3 ligase ligand-linker conjugate, incorporating a cereblon ligand based on Thalidomide and a linker component commonly used in PROTAC technology.

Methyltetrazine-PEG5-alkyne, a PEG-based PROTAC linker, is utilized in synthesizing PROTACs[1].

Methyltetrazine-amido-PEG7-azide is a PEG-based PROTAC linker used for synthesizing PROTACs[1].

Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2 is a synthesized E3 ligase ligand-linker, incorporating a cereblon ligand based on Thalidomide and a 3-unit PEG linker, specifically designed for PROTAC technology applications.

Methyltetrazine-PEG5-methyltetrazine is a PEG-based PROTAC linker used in the synthesis of PROTACs [1].

Methyltetrazine-PEG5-triethoxysilane is a polyethylene glycol (PEG)-based PROTAC linker suitable for PROTAC synthesis[1].