Name: MPI8
Brand: TargetMol
SKU: T68541
Rating: 4.5 (1 reviews)

Pack Size

Price

Availability

Quantity

25 mg

$1,820

8-10 weeks

50 mg

$2,380

8-10 weeks

100 mg

$3,100

8-10 weeks

QWhether TargetMol inhibitor products are suitable for industrial use?

AThere are various standards for defining the purity, and we do not have fixed purity standard. The purity of most products are above 98% and can be used for control experiments, including cell experiments, animal experiments, general laboratory experiments, and high-throughput screening. Our product purity also meets the industrial standard.

QWhether sonication is needed for product dissolution? What if I don't have an ultrasound machine?

Asonication can accelerate dissolution. If the compound is not dissolving, sonication is recommended. If you don't have an ultrasound machine, a lower solvent concentration or using less powder are recommended.

QIf the product does not dissolve even when it is below the maximum solubility stated in the instructions, what should I do?

AIt is recommended to utilize some auxiliary dissolution methods, such as heating to 45°C or using sonication to accelerate dissolution.

QHow to choose the appropriate solvent?

ACommon solvents include DMSO, water, ethanol, etc. Please select the appropriate solvent according to the solubility reference. If the inhibitor can be dissolved in DMSO, it is recommended to use freshly opened DMSO without moisture absorption. If the inhibitor can be dissolved in water, solvents like sterile water, physiological saline, sterile PBS ahd culture medium are recommended.

QThe detection results after adding the drug show no effect. Does this indicate a problem with the product quality?

AThe product quality is assured, All products have undergone two rigorous quality inspections. Structural confirmation is achieved through HNMR, while purity is determined by HPLC. However, the same inhibitor may yield different IC50 values and experimental outcomes due to variations in experimental materials (such as cells or animals). Therefore, it's not advisable to directly replicate methods in literature. Instead, establish concentration gradients tailored to your own experiments.

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.