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Ms-PEG12-Boc, a PEG-based linker for PROTACs, connects two essential ligands necessary for creating PROTAC molecules, facilitating selective protein degradation via the ubiquitin-proteasome system within cells.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Ms-PEG12-Boc, a PEG-based linker for PROTACs, connects two essential ligands necessary for creating PROTAC molecules, facilitating selective protein degradation via the ubiquitin-proteasome system within cells. |
In vitro | PROTACs, composed of two distinct ligands connected by a linker, target proteins for degradation via the intracellular ubiquitin-proteasome system. One ligand binds to an E3 ubiquitin ligase, while the other binds to the target protein[1]. |
Molecular Weight | 752.91 |
Formula | C32H64O17S |
Relative Density. | 1.31g/cm3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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