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MS15

Catalog No. T74983

MS15 is a potent, selective degrader of AKT PROTAC, effectively inhibiting activities of AKT1, AKT2, and AKT3. It exhibits IC50 values of 798 nM for AKT1, 90 nM for AKT2, and 544 nM for AKT3, respectively [1].

MS15
Other Forms of MS15:
MS15 TFAT77968
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MS15

Catalog No. T74983
MS15 is a potent, selective degrader of AKT PROTAC, effectively inhibiting activities of AKT1, AKT2, and AKT3. It exhibits IC50 values of 798 nM for AKT1, 90 nM for AKT2, and 544 nM for AKT3, respectively [1].
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Product Introduction

Bioactivity
Description
MS15 is a potent, selective degrader of AKT PROTAC, effectively inhibiting activities of AKT1, AKT2, and AKT3. It exhibits IC50 values of 798 nM for AKT1, 90 nM for AKT2, and 544 nM for AKT3, respectively [1].
Chemical Properties
Molecular Weight1114.45
FormulaC64H79N11O5S
Storage & Solubility Information
StorageShipping with blue ice.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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