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Mulberrofuran Q is an active compound that inhibits the formation of 12-hydroxy-5,8,10-heptadecatrienoic acid (HHT) and thromboxane B2 (cyclooxygenase product) , which protects neuronal cells from hypoxia-glycorrhoea-deficiency (OGD)-induced oxidative stress.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $124 | In Stock | |
10 mg | $481 | In Stock | |
1 mL x 10 mM (in DMSO) | $620 | In Stock |
Description | Mulberrofuran Q is an active compound that inhibits the formation of 12-hydroxy-5,8,10-heptadecatrienoic acid (HHT) and thromboxane B2 (cyclooxygenase product) , which protects neuronal cells from hypoxia-glycorrhoea-deficiency (OGD)-induced oxidative stress. |
In vitro | The effects of various phenolic compounds isolated from the rootbark of the mulberry tree on rat platelet cyclooxygenase and lipoxygenase products formed from (1-14C)arachiodonic acid were studied. Kuwanons G and H, sanggenon C, and mulberrofuran Q at concentrations of 10(-3) to 10(-4)M inhibited the formation of 12-hydroxy-5,8,10-heptadecatrienoic acid (HHT) and thromboxane B2 (cyclooxygenase products); however, they increased the formation of 12-hydroxy-5,8,10,14-eicosatetraenoic acid (12-HETE) (a lipoxygenase product).[2] |
Alias | MulberrofuranQ |
Molecular Weight | 592.55 |
Formula | C34H24O10 |
Cas No. | 101383-35-1 |
Smiles | O=C1C2C3(C(O3)(OC=4C2=C(O)C=C(C4)C=5OC=6C(C5)=CC=C(O)C6)C7=C(O)C=C(O)C=C7)C8C=9C(OC1(C)C8)=CC(O)=CC9 |
Relative Density. | 1.75 g/cm3 (Predicted) |
Storage | keep away from direct sunlight,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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