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N-dodecanoyl-L-Homoserine lactone

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Catalog No. T13789Cas No. 137173-46-7
Alias C12-HSL

N-dodecanoyl-L-Homoserine lactone (C12-HSL) is a quorum sensing (QS) signaling molecule that impacts biofilm formation in bioreactors through acyl homoserine lactone (AHL) mediated microbial communication.

N-dodecanoyl-L-Homoserine lactone

N-dodecanoyl-L-Homoserine lactone

🥰Excellent
Purity: 99.80%
Catalog No. T13789Alias C12-HSLCas No. 137173-46-7
N-dodecanoyl-L-Homoserine lactone (C12-HSL) is a quorum sensing (QS) signaling molecule that impacts biofilm formation in bioreactors through acyl homoserine lactone (AHL) mediated microbial communication.
Pack SizePriceAvailabilityQuantity
5 mg$39In Stock
10 mg$64In Stock
25 mg$123In Stock
50 mg$228In Stock
100 mg$372In Stock
1 mL x 10 mM (in DMSO)$43In Stock
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Purity:99.80%
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Product Introduction

Bioactivity
Description
N-dodecanoyl-L-Homoserine lactone (C12-HSL) is a quorum sensing (QS) signaling molecule that impacts biofilm formation in bioreactors through acyl homoserine lactone (AHL) mediated microbial communication.
In vitro
N-dodecanoyl-L-Homoserine lactone inhibits IgE dependent and independent degranulation and mediator release from primary mast cells[1].
AliasC12-HSL
Chemical Properties
Molecular Weight283.41
FormulaC16H29NO3
Cas No.137173-46-7
SmilesCCCCCCCCCCCC(=O)N[C@H]1CCOC1=O
Relative Density.1.00 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 25 mg/mL (88.21 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.5285 mL17.6423 mL35.2846 mL176.4229 mL
5 mM0.7057 mL3.5285 mL7.0569 mL35.2846 mL
10 mM0.3528 mL1.7642 mL3.5285 mL17.6423 mL
20 mM0.1764 mL0.8821 mL1.7642 mL8.8211 mL
50 mM0.0706 mL0.3528 mL0.7057 mL3.5285 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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