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NDM-1 inhibitor-3

🥰Excellent
Catalog No. T60454

NDM-1 inhibitor-3 is a New Delhi Metallo-β-lactamase-1 (NDM-1) inhibitor (Ki : 4 μM) widely found in nature and is associated with antibiotic resistance.

NDM-1 inhibitor-3

NDM-1 inhibitor-3

🥰Excellent
Purity: 98.66%
Catalog No. T60454
NDM-1 inhibitor-3 is a New Delhi Metallo-β-lactamase-1 (NDM-1) inhibitor (Ki : 4 μM) widely found in nature and is associated with antibiotic resistance.
Pack SizePriceAvailabilityQuantity
1 mg$38In Stock
5 mg$89In Stock
10 mg$148In Stock
25 mg$293In Stock
50 mg$488In Stock
100 mg$712In Stock
500 mg$1,480In Stock
1 mL x 10 mM (in DMSO)$87In Stock
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Purity:98.66%
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Product Introduction

Bioactivity
Description
NDM-1 inhibitor-3 is a New Delhi Metallo-β-lactamase-1 (NDM-1) inhibitor (Ki : 4 μM) widely found in nature and is associated with antibiotic resistance.
Targets&IC50
NDM1:4 μM(Ki)
In vitro
New Delhi Metallo-β-lactamase-1 (NDM-1), an acquired metallo-carbapenemase first identified in 2009, is now regarded as a highly significant target for developing β-lactam-β-lactamase inhibitor combinations effective against NDM-producing clinical isolates.
Chemical Properties
Molecular Weight268.26
FormulaC16H12O4
SmilesO=C1C2=C(O)C=CC=C2C/C1=C\C3=CC(O)=C(O)C=C3
Storage & Solubility Information
StorageShipping with blue ice.
Solubility Information
DMSO: 50 mg/mL (186.39 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.7277 mL18.6386 mL37.2773 mL186.3863 mL
5 mM0.7455 mL3.7277 mL7.4555 mL37.2773 mL
10 mM0.3728 mL1.8639 mL3.7277 mL18.6386 mL
20 mM0.1864 mL0.9319 mL1.8639 mL9.3193 mL
50 mM0.0746 mL0.3728 mL0.7455 mL3.7277 mL
100 mM0.0373 mL0.1864 mL0.3728 mL1.8639 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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2 Enter the in vivo formulation:
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