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Neurokinin antagonist 1
🥰Excellent
Catalog No. T10056Cas No. 214487-45-3
Neurokinin antagonist 1 is a potent is a neuropeptide antagonist that can be used to study neurological disorders.
Neurokinin antagonist 1
🥰Excellent
Purity: 100%
Catalog No. T10056Cas No. 214487-45-3
Neurokinin antagonist 1 is a potent is a neuropeptide antagonist that can be used to study neurological disorders.
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Purity:100%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Neurokinin antagonist 1 is a potent is a neuropeptide antagonist that can be used to study neurological disorders. |
| In vitro | The invention described in patent WO1998045262A1 pertains to antagonists of the interaction between the P substance and the NK-1 receptor, their preparation process, and their utilization in pharmaceutical compositions. These compositions may be employed in the treatment of pathological conditions involving the P substance receptor, specifically in the management of airway inflammation, such as asthma and rhinitis, as well as in the treatment of emesis[1]. |
| Molecular Weight | 600.75 |
| Formula | C38H40N4O3 |
| Cas No. | 214487-45-3 |
| Smiles | C(N[C@H]1[C@@H](NC([C@@H](CC2=CC3=C(C=C2)C=CC=C3)N(C(CC4=CC=C(C)C=C4)=O)C)=O)CCCC1)(=O)C=5C=6C(NC5)=CC=CC6 |
| Relative Density. | 1.26 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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