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ONO4057 is a potent and orally active Leukotriene B4 receptor antagonist with an IC50 value of 0.7±0.3 μM. Immunosuppressive effect of ONO4057 on rat allografts.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $700 | 6-8 weeks | |
5 mg | $1,800 | 6-8 weeks |
Description | ONO4057 is a potent and orally active Leukotriene B4 receptor antagonist with an IC50 value of 0.7±0.3 μM. Immunosuppressive effect of ONO4057 on rat allografts. |
Targets&IC50 | LTB4:0.7 μM |
In vivo | The mean animal survivals of ONO4057-treated animals significantly prolong to 21.0±4.4 days compared with 12.0±0.6 days in the control group. Histological findings from grafts taken on day 7 show that severe focal cellular infiltration is observed in both groups, but the degree of hepatocyte necrosis in ONO4057-treated animals is milder than that in the control group[1]. |
Alias | ONO-LB457 |
Molecular Weight | 470.55 |
Formula | C27H34O7 |
Cas No. | 134578-96-4 |
Smiles | C(CC(O)=O)C1=C(OCCCCC(O)=O)C=CC=C1OCCCC/C=C/C2=CC=C(OC)C=C2 |
Relative Density. | 1.173 g/cm3 (Predicted) |
Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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