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PARP1-IN-12

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Catalog No. T73023

PARP1-IN-12, a potent inhibitor of PARP1, demonstrates an IC50 value of 2.99 nM. It exhibits antiproliferative effects, induces apoptosis, and causes cell cycle arrest in the G2/M phase. Additionally, PARP1-IN-12 induces DNA double-strand breaks (DSBs) in BRCA-deficient cells.

PARP1-IN-12

PARP1-IN-12

😃Good
Catalog No. T73023
PARP1-IN-12, a potent inhibitor of PARP1, demonstrates an IC50 value of 2.99 nM. It exhibits antiproliferative effects, induces apoptosis, and causes cell cycle arrest in the G2/M phase. Additionally, PARP1-IN-12 induces DNA double-strand breaks (DSBs) in BRCA-deficient cells.
Pack SizePriceAvailabilityQuantity
25 mg$2,72010-14 weeks
50 mg$3,58010-14 weeks
100 mg$4,90010-14 weeks
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Product Introduction

Bioactivity
Description
PARP1-IN-12, a potent inhibitor of PARP1, demonstrates an IC50 value of 2.99 nM. It exhibits antiproliferative effects, induces apoptosis, and causes cell cycle arrest in the G2/M phase. Additionally, PARP1-IN-12 induces DNA double-strand breaks (DSBs) in BRCA-deficient cells.
Chemical Properties
Molecular Weight741.93
FormulaC43H56FN5O5
Storage & Solubility Information
StorageShipping with blue ice.

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