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PF-06260933 HCl

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Catalog No. T33945Cas No. 1883548-86-4
Alias PF-06260933 dihydrochloride, PF06260933 dihydrochloride, PF 06260933 dihydrochloride

PF-06260933 Dihydrochloride is a MAP4K4 (HGK) inhibitor (IC50 = 140 nM). It can improve the fasting hyperglycemia in mice. In addition, it inhibited Mink and Tnik (IC50 values of 8 and 13 nM, respectively).

PF-06260933 HCl
Other Forms of PF-06260933 HCl:

PF-06260933 HCl

😃Good
Catalog No. T33945Alias PF-06260933 dihydrochloride, PF06260933 dihydrochloride, PF 06260933 dihydrochlorideCas No. 1883548-86-4
PF-06260933 Dihydrochloride is a MAP4K4 (HGK) inhibitor (IC50 = 140 nM). It can improve the fasting hyperglycemia in mice. In addition, it inhibited Mink and Tnik (IC50 values of 8 and 13 nM, respectively).
Pack SizePriceAvailabilityQuantity
10 mg$56335 days
50 mg$2,35035 days
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Product Introduction

Bioactivity
Description
PF-06260933 Dihydrochloride is a MAP4K4 (HGK) inhibitor (IC50 = 140 nM). It can improve the fasting hyperglycemia in mice. In addition, it inhibited Mink and Tnik (IC50 values of 8 and 13 nM, respectively).
AliasPF-06260933 dihydrochloride, PF06260933 dihydrochloride, PF 06260933 dihydrochloride
Chemical Properties
Molecular Weight369.68
FormulaC16H15Cl3N4
Cas No.1883548-86-4
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

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