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PiB

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Purity:97.02%

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COA HPLC HNMR

PiB

Catalog No. T21000Cas No. 566169-93-5

PiB (Pittsburgh Compound-B) is a standard for analysis of 11C-PiB. 11C-PiB is a β-amyloid PET imaging tracer for Alzheimer's disease diagnosis.

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Pack Size	Price	Availability
1 mg	$37	In Stock
2 mg	$50	In Stock
5 mg	$72	In Stock
10 mg	$98	In Stock
25 mg	$183	In Stock
50 mg	$276	In Stock
100 mg	$413	In Stock
1 mL x 10 mM (in DMSO)	$79	In Stock

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Product Introduction

Bioactivity

Description	PiB (Pittsburgh Compound-B) is a standard for analysis of 11C-PiB. 11C-PiB is a β-amyloid PET imaging tracer for Alzheimer's disease diagnosis.
Alias	Pittsburgh Compound-B, 6-OH-BTA-1

Chemical Properties

Molecular Weight	256.32
Formula	C14H12N2OS
Cas No.	566169-93-5

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 60 mg/ml (234.08 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.9014 mL	19.5069 mL	39.0137 mL	195.0687 mL
5 mM	0.7803 mL	3.9014 mL	7.8027 mL	39.0137 mL
10 mM	0.3901 mL	1.9507 mL	3.9014 mL	19.5069 mL
20 mM	0.1951 mL	0.9753 mL	1.9507 mL	9.7534 mL
50 mM	0.0780 mL	0.3901 mL	0.7803 mL	3.9014 mL
100 mM	0.0390 mL	0.1951 mL	0.3901 mL	1.9507 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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