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Pomalidomide-6-O-CH3

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Catalog No. T39033Cas No. 1547163-08-5
Alias Pomalidomide-6-O-CH3

Pomalidomide-6-O-CH3 is a Pomalidomide-derived ligand for cereblon (CRBN), which serves as a linkage agent to recruit the CRBN protein. This ligand, when connected to a protein via a linker, enables the formation of PROTAC.

Pomalidomide-6-O-CH3

Pomalidomide-6-O-CH3

😃Good
Catalog No. T39033Alias Pomalidomide-6-O-CH3Cas No. 1547163-08-5
Pomalidomide-6-O-CH3 is a Pomalidomide-derived ligand for cereblon (CRBN), which serves as a linkage agent to recruit the CRBN protein. This ligand, when connected to a protein via a linker, enables the formation of PROTAC.
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Product Introduction

Bioactivity
Description
Pomalidomide-6-O-CH3 is a Pomalidomide-derived ligand for cereblon (CRBN), which serves as a linkage agent to recruit the CRBN protein. This ligand, when connected to a protein via a linker, enables the formation of PROTAC.
In vitro
PROTACs consist of two distinct ligands joined by a linker: one targets an E3 ubiquitin ligase and the other targets a specific protein. By utilizing the intracellular ubiquitin-proteasome system, PROTACs selectively degrade target proteins[1].
AliasPomalidomide-6-O-CH3
Chemical Properties
Molecular Weight303.274
FormulaC14H13N3O5
Cas No.1547163-08-5
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Keywords

Pomalidomide 6 O CH3Pomalidomide-6-O-CH-3Pomalidomide6OCH3
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