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Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $389 | Backorder | |
50 mg | $617 | Backorder | |
100 mg | $979 | Backorder | |
200 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Pomalidomide-amino-PEG4-NH2 hydrochloride, a synthesized E3 ligase ligand-linker conjugate, incorporates the cereblon ligand derived from Pomalidomide, along with a linker commonly employed in PROTAC technology. |
In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
Alias | Pomalidomide-amino-PEG4-NH2 hydrochloride |
Molecular Weight | 542.97 |
Formula | C23H31ClN4O9 |
Cas No. | 2331259-45-9 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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