pomalidomide-amino-peg4-nh2 hydrochloride

Pomalidomide-amino-PEG4-NH2 hydrochloride, a synthesized E3 ligase ligand-linker conjugate, incorporates the cereblon ligand derived from Pomalidomide, along with a linker commonly employed in PROTAC technology.

2-(2,6-dioxopiperidin-3-yl)-4-((7-hydrox is protac.

Butanoic acid, 4-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- (4-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]butanoic acid) is a Cereblon ligand with alkyl linker and terminal acid for onward chemistry.

Thalidomide-NH-PEG1-NH2 hydrochloride (4-[(2-(2-Aminoethoxy)ethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl) is a synthetic E3 ligase ligand-linker conjugate that incorporates the Thalidomide-based cereblon ligand and a linker[1].

Pomalidomide-PEG2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based CRBN ligand and linker used in PROTAC technology.

Thalidomide-NH-(CH2)2-NH2 TFA is an alkyl-modified derivative of Thalidomide serving as a Cereblon ligand to recruit CRBN proteins and a pivotal intermediate in the synthesis of CRBN-based PROTAC molecules for the targeted small molecule PROTACs aimed at SHP2 protein.

Amino-Tri-(carboxyethoxymethyl)-methane hydrochloride is a cleavable PEG-based linker employed in the synthesis of antibody-drug conjugates (ADCs) and utilized as a PEG-based PROTAC linker for PROTACs synthesis, as documented in references [1] [2].

SNIPER(TACC3)-2 hydrochloride is a compound that induces degradation of the TACC3 protein through the ubiquitin-proteasome pathway by exploiting an IAP ligand, leading to the induction of cancer cell death [1].

Pomalidomide-C7-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based CRBN ligand and linker used in PROTAC technology.

(S,R,S)-AHPC-(C3- PEG) 2- C6- Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker. (S,R,S)-AHPC-(C3- PEG) 2- C6- Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays[1].

Pomalidomide-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate. Pomalidomide-C2-NH2 hydrochloride incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.

Pomalidomide-amino-PEG3-NH2 is a compound obtained through synthesis, consisting of a conjugation between the E3 ligase ligand linker and Pomalidomide, a cereblon ligand. This compound is specifically designed for application in PROTAC technology, incorporating a linker that enables effective binding with the targeted proteins.

Pomalidomide-amino-PEG4-NH2 is a conjugate compound that combines the Pomalidomide-based cereblon ligand and a linker, effectively functioning as a synthesized E3 ligase ligand-linker conjugate utilized in PROTAC technology.

4-(N-Boc-amino)-1,6-heptanedioic acid is an alkyl/ether-based linker, suitable for PROTAC synthesis [1].

Functionalized cereblon ligand for PROTAC research and development; incorporates an E3 ligase ligand plus an alkylC8 linker with terminal acid ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

Pomalidomide-amino-PEG5-NH2 is a synthesized conjugate combining the Pomalidomide-based cereblon ligand and a linker utilized in PROTAC technology. It acts as an E3 ligase ligand-linker conjugate.

Pomalidomide-C6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based CRBN ligand and linker used in PROTAC technology.

2-(2-(6-chlorohexyloxy)ethoxy)ethanamine hydrochloride is a useful organic compound for research related to life sciences and the catalog number is T64585.

Pomalidomide-PEG4-C2-NH2 hydrochloride is a PEG-based PROTAC linker that can be used to synthesize PROTACs[1].

Pomalidomide-C11-NH2 hydrochloride is a cereblon (CRBN) ligand derived from Pomalidomide used to recruit the CRBN protein. This compound can be conjugated with a linker to the protein ligand to assemble a PROTAC [1].

Pomalidomide-5-C10-NH2 hydrochloride, a Pomalidomide-derived cereblon (CRBN) ligand, facilitates the recruitment of CRBN protein. This compound can be tethered to a protein ligand via a linker to construct a PROTAC [1].

Pomalidomide-5-C11-NH2 hydrochloride is a Pomalidomide-derived cereblon (CRBN) ligand that facilitates the recruitment of the CRBN protein. This compound can be conjugated to a protein ligand via a linker to create a PROTAC [1].

Thalidomide-NH-C10-NH2 hydrochloride, a thalidomide-derived cereblon ligand, facilitates CRBN protein recruitment and, when conjugated with a linker, forms PROTACs [1].

Pomalidomide-5-C8-NH2 hydrochloride, a Pomalidomide-based cereblon (CRBN) ligand, is instrumental in the recruitment of CRBN protein. This compound can be linked to the protein ligand via a linker to form PROTAC [1].

Thalidomide-5-NH-PEG1-NH2 hydrochloride is a Thalidomide-based cereblon ligand designed for CRBN protein recruitment. It facilitates the formation of PROTAC molecules by linking to target protein ligands, such as THAL-SNS-032, via a connector.

Pomalidomide 4'-alkylC6-azide, a Pomalidomide-based cereblon (CRBN) ligand, facilitates the recruitment of CRBN protein. It is designed to attach to a protein through a linker, enabling the formation of PROTAC [1].

Pomalidomide-amino-PEG5-NH2 hydrochloride is a chemical compound that has been synthesized as an E3 ligase ligand-linker conjugate. This compound combines a Pomalidomide-based cereblon ligand with a linker commonly used in PROTAC technology.

cis-4-Hydroxy-D-proline hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T66933 and the CAS number is 77449-94-6.

Pomalidomide-C2-amido-(C1-O-C5-O-C1)2-COOH is a chemically synthesized compound, designed as an E3 ligase ligand-linker conjugate, integrating the cereblon ligand derived from Pomalidomide and a linker employed in PROTAC technology. This compound serves to facilitate targeted protein degradation through the modulation of E3 ligase activity, enabling the selective elimination of specific proteins of interest.

Pomalidomide-amido-C4-amido-C6-NH-Boc, a synthesized conjugate, is a ligand-linker incorporating the cereblon ligand based on Pomalidomide and a PROTAC technology linker.

tans-4-Hydroxy-D-proline hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T65471 and the CAS number is 142347-81-7.

Thalidomide-4-O-C11-NH2 hydrochloride is a thalidomide-based cereblon ligand for CRBN protein recruitment. It can be conjugated to a protein ligand via a linker to create PROTACs [1].

Thalidomide-4-O-C12-NH2 hydrochloride is a cereblon ligand based on Thalidomide, utilized for recruiting the CRBN protein. This compound can be tethered to a protein ligand using a linker, enabling the formation of PROTACs [1].

Thalidomide-NH-C9-NH2 hydrochloride, a Thalidomide-based cereblon ligand, facilitates the recruitment of CRBN protein. This compound can be conjugated to a protein-targeting ligand via a linker, enabling the formation of proteolysis-targeting chimeras (PROTACs) [1].

Pomalidomide-PEG3-C2-NH2 hydrochloride, also known as Cereblon Ligand-Linker Conjugate 5, is a chemically synthesized E3 ligase ligand-linker conjugate. This compound incorporates a cereblon ligand based on Pomalidomide and a linker commonly employed in PROTAC technology.

Thalidomide-5-NH-PEG2-NH2 hydrochloride is a cereblon ligand based on Thalidomide, designed to recruit CRBN proteins. It has the capability to be linked with target protein ligands via a linker, facilitating the formation of PROTAC molecules, such as THAL-SNS-032.

Thalidomide-O-amido-PEG-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker. Thalidomide-O-amido-PEG-C2-NH2 hydrochloride can be used in the synthesis of PROTACs.

cis-4-Hydroxy-L-proline hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T65954 and the CAS number is 441067-49-8.

Pomalidomide-C4-NH2 hydrochloride is a synthesized conjugate comprising an E3 ligase ligand-linker. This compound incorporates the cereblon ligand derived from Pomalidomide and a linker that is commonly employed in PROTAC technology.

Ph-Bis(C1-N-(C2-NH-Boc)2) is a versatile alkyl chain-derived linker employed in the synthesis of PROTACs[1].

Thalidomide-4-O-C10-NH2 hydrochloride, a Thalidomide-based cereblon ligand, facilitates the recruitment of the CRBN protein. This compound can be conjugated with a protein ligand via a linker to synthesize PROTACs [1].

Thalidomide-NH-CBP/p300 ligand 2 (P-007) is a PROTAC-based compound designed to degrade CBP and p300, acting as a functional antagonist (WO2020173440).

cIAP1 Ligand-Linker Conjugates 2 Hydrochloride is a chemical compound that combines an IAP ligand, which targets the E3 ubiquitin ligase, with a PROTAC linker. It is utilized in the creation of SNIPERs[1].

4-Boc-amino-22-dimethylbutyric acid is an alkyl/ether-derived PROTAC linker, suitable for the synthesis of PROTACs.

Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2 is a synthetic conjugate compound that combines a Thalidomide-based cereblon ligand and a linker, which is commonly utilized in PROTAC technology. This compound acts as a connector between the target protein and the E3 ligase, facilitating targeted protein degradation.

Pomalidomide-PEG6-NH2 hydrochloride is a compound resulting from the synthesis of an E3 ligase ligand-linker conjugate. It combines the cereblon ligand derived from Pomalidomide with a 6-unit PEG linker. This compound is specifically designed for application in PROTAC technology.

DSPE-PEG-2-Aminoethyl-alpha-mannopyranoside (MW 2000) is a polyethylene glycol (PEG) derived linker. This specific linker is utilized in the synthesis of PROTACs, or proteolysis targeting chimeras [1].

Thalidomide 4'-ether-alkylC2-amine hydrochloride (halidomide-linker 6) is a synthesized E3 ligase ligand-linker conjugate.

Thalidomide-4-C3-NH2 hydrochloride is a Thalidomide-derived cereblon ligand utilized for the recruitment of CRBN protein. This compound can be linked to the ligand for protein using a linker to create PROTACs.