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Prexasertib Mesylate Hydrate (LY2606368 Mesylate Hydrate) is an ATP-competitive, selective, second-generation cell cycle checkpoint kinase 1 (CHK1) inhibitor (IC50<1 nM, Ki: 0.9 nM). It inhibits CHK2 (IC50: 8 nM) and RSK1 (IC50: 9 nM), induces double-stranded DNA breaks and replication mutations, triggers apoptosis, and exhibits potent anti-tumor effects.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | 1.444 € | 1-2 weeks | |
50 mg | 1.881 € | 1-2 weeks | |
100 mg | 2.375 € | 1-2 weeks |
Description | Prexasertib Mesylate Hydrate (LY2606368 Mesylate Hydrate) is an ATP-competitive, selective, second-generation cell cycle checkpoint kinase 1 (CHK1) inhibitor (IC50<1 nM, Ki: 0.9 nM). It inhibits CHK2 (IC50: 8 nM) and RSK1 (IC50: 9 nM), induces double-stranded DNA breaks and replication mutations, triggers apoptosis, and exhibits potent anti-tumor effects. |
Molecular Weight | 479.51 |
Formula | C19H25N7O6S |
Cas No. | 1234015-57-6 |
Storage | Shipping with blue ice. |
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