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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | Inquiry | Backorder | |
50 mg | Inquiry | Backorder |
Description | rTRD01 is a TDP-43 ligand that selectively binds to the RRM1 and RRM2 domains of TDP-43, exhibiting a dissociation constant (Kd) of 89 µM for TDP-43 102–269. This compound is capable of partially disrupting the interaction between TDP-43 and the hexanucleotide RNA repeat associated with the c9orf72 gene, which is implicated in certain neurodegenerative diseases. rTRD01 holds potential for use in neurodegenerative disease research [1]. |
Molecular Weight | 344.38 |
Formula | C18H21FN4O2 |
Cas No. | 1332175-56-0 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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