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Saprorthoquinone
Catalog No. TN6425Cas No. 102607-41-0
Saprorthoquinone is a natural product from Salvia prionitis.
Saprorthoquinone
Catalog No. TN6425Cas No. 102607-41-0
Saprorthoquinone is a natural product from Salvia prionitis.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $1,090 | Backorder | |
| 1 mL x 10 mM (in DMSO) | $1,110 | Backorder |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Saprorthoquinone is a natural product from Salvia prionitis. |
| In vitro | Ten diterpenoids [6a-hydroxysalvinolone (1 ), 6a-hydroxytaxodone (2 ), aethiopinone (3 ), microstegiol (4 ), ferruginol (5 ), Saprorthoquinone (6 ), 11,12-dioxoabieta-8,13-diene (7 ), taxodione (8 ), hypargenin A (9 ), hypargenin D (10 )] and three triterpenoids [lupeol 3-acetate, d-oleanol 3-acetate and -sitosterol] were isolated from the roots of Salvia hypargeia , a plant endemic to Turkey. METHODS AND RESULTS: The crude extract and compounds 1-2 , 5-10 were tested against a panel of human cancer cell lines [human breast cancer (BC 1), human lung cancer (LU 2), human colon cancer (COL 2), human epidermoidal carcinoma in mouth (KB), vinblastine-resistant KB-VI, hormone-dependent human prostate cancer (LNCaP)] as well as P388 and ASK cells in culture. CONCLUSIONS: The crude extract was active in all of the test systems, except KB. Isolates 1 and 8 were also found to mediate a generalized cytotoxic response. |
| Molecular Weight | 296.4 |
| Formula | C20H24O2 |
| Cas No. | 102607-41-0 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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