Tanshinone IIA sulfonate sodium (Tanshinone IIA sodium sulfonate) is a water-soluble derivative of tanshinone IIA extracted from Savia miltiorrhiza; a potent negative allosteric modulator of the human purinergic receptor P2X7. Tanshinone IIA sulfonate sodium (12.5 μM) inhibits hypoxia-induced PKG and PPAR-γ downregulation in PASMCs and distal pulmonary arteries of rats.

Ro 09-0680, a compound derived from Salvia miltiorrhiza, is a potent inhibitor of collagen-induced platelet aggregation in rabbits with potential anti-inflammatory activity for the study of cardiovascular disease.

Tanshinone IIA (Tanshinone B) is a diterpene quinone natural product that targets the protein kinase domain of VEGF VEGFR2. Tanshinone IIA inhibits angiogenesis and exhibits anti-inflammatory, antioxidant, and therapeutic activities against coronary heart disease.

Salvianolic acid D ((R,E)-2-((3-(2-(carboxymethyl)-3,4-dihydroxyphenyl)acryloyl)oxy)-3-(3,4-dihydroxyphenyl)propanoic acid) and notoginseng triterpenes can promote EA-hy926 and expression of protein with protective effects on angiogenesis in EA-hy926 cells in vitro.

Dibutyl phthalate (1,2-Benzenedicarboxylic acid) is a plasticizer, commonly used in industrial manufacturing, that causes cardiac damage by disrupting Ca(2+) transfer from the endoplasmic reticulum to the mitochondria and triggering subsequent cellular death.Dibutyl phthalate induces oxidative damage in the brain of zebrafish.

Royleanone possesses cytotoxic activity against the human pancreatic cancer cell line MIA PaCa-2.

Danshenxinkun C is a natural product for research related to life sciences. The catalog number is TN3762 and the CAS number is 65907-77-9.

Dihydroisotanshinone II is a natural product for research related to life sciences. The catalog number is TN3851 and the CAS number is 260397-58-8.

Camaldulenic acid is a natural product of Salvia, Lamiaceae. The catalog number is TN5954 and the CAS number is 71850-15-2. Camaldulenic acid can be used as a reference standard.

Tanshinlactone is a natural product of Salvia, Lamiaceae. The catalog number is TN5098 and the CAS number is 105351-70-0. Tanshinlactone can be used as a reference standard.

Neocryptotanshinone inhibits rabbit platelet aggregation induced by arachidonic acid.

Methylenetanshinquinone shows antiplasmodial and antitrypanosomal activity, it is active against both Trypanosoma brucei rhodesiense and Plasmodium falciparum.

Danshenol C is a natural product of Salvia, Lamiaceae. The catalog number is TN3761 and the CAS number is 910856-25-6. Danshenol C can be used as a reference standard.

Isosalvipuberulin is a natural product of Salvia, Lamiaceae. The catalog number is TN5568 and the CAS number is 115321-32-9. Isosalvipuberulin can be used as a reference standard.

Tanshindiol A, a natural product of Salvia (Lamiaceae), has the catalog number TN5095 and the CAS number 97411-46-6. It can be used as a reference standard.

4-Hydroxy-2,6,6-trimethyl-1-cyclohexene is a natural product for research related to life sciences. The catalog number is TN3034 and the CAS number is 62218-55-7.

Co-treatment with Tanshinone IIB (TSB) significantly inhibits the DNA laddering, cytotoxicity and apoptosis of rat cortical neurons induced by staurosporine in a concentration-dependent manner; TSB also suppresses the elevated Bax protein and decreased bc

Sageone represents a promising anticancer agent against gastric cancer that warrants further study, it synergizes with cisplatin cytotoxicity in SNU-1 human gastric cancer cells.Sageone also shows antiviral activity.

(+)-1-Hydroxypinoresinol 1-O-beta-D-glucoside exhibits peroxynitrite, total ROS and DPPH radical scavenging activities with IC50 values of 3.23 + - 0.04, 2.26 + - 0.07 and 32.3 + - 0.13 microM, respectively.

Horminone has antimicrobial activity, it can inhibit the protein synthesis in several types of bacteria; it can inhibit the in vitro growth of Trypanosoma cruzi, 30 microM drug concentration producing total inhibition of growth. After administration of plant extracts containing Horminone has possibility of toxic effect.

Hydroxytanshinone ⅡA has good antiproliferative effect on SGC-7901,HeLa, and HepG 2 cell, the values of IC50 are 4.18, 6.08 and10.20 uM, respectively; it has tumor cell proliferation inhibition significantly stronger than the tanshinoneⅡA.

Virgatic acid is a natural product from Salvia virgafa.

13-Epimanool is a natural product of Salvia, Lamiaceae. The catalog number is TN2611 and the CAS number is 1438-62-6. 13-Epimanool can be used as a reference standard.

Przewalskinic acid A is a rare, water-soluble, and highly biologically active ingredient found, thus far, only in the Salvia przewalskii Maxim herb.

Danshenol A has strong aldose reductase (AR) inhibitory activity, has IC50 of 0.10 microM which is comparable to that of epalrestat in clinical use. Danshenol A also has antitumor activity in T-24, QGY, K562, Me180 and BIU87 cell lines, shows inhibited growth of K562 (IC50 = 0.53 μg mL), T-24 (IC50 = 7.94 μg mL), QGY (IC50 = 4.65 μg mL) and Me180 (IC50 = 6.89 μg mL) cell lines.

Danshenxinkun D has antituberculosis H_(37)Rv activity in vitro.

20-Deoxocarnosol has antioxidant activity of measuring the decay of the radical cation diphenyl-picrylhydrazyl (DPPH).It also exhibits non-specific antiprotozoal activity due to high cytotoxicity.

1,2 Dihydrotanshinquinone is active against both Trypanosoma brucei rhodesiense and Plasmodium falciparum.

Methyl salvionolate A has anti-HIV-1 activity.

Neocryptotanshinone inhibits lipopolysaccharide-induced inflammation in RAW264.7 macrophages by suppression of NF-κB and iNOS signaling pathways.

Isocryptotanshinone inhibits protein tyrosine phosphatase 1B (PTP1B) activity with 50% inhibitory concentration values of 56.1±6.3 μM, PTP1B acts as a negative regulator of insulin signaling, and selective inhibition of PTP1B has served as a potential drug target for the treatment of type 2 diabetes.

Dihydroisotanshinone I has protective action against menadione-induced hepatotoxicity, attributed to its antioxidant properties including the free radical scavenging activity and inhibition of lipid peroxidation.

Tanshindiol B possesses a unique anti-cancer activity whose mechanism involves the inhibition of EZH2 activity and would provide chemically valuable information for designing a new class of potent EZH2 inhibitors. It also possesses the anti-angiogenic act

Prionitin is a natural product from Salvia prionitis Hance.

Saprorthoquinone is a natural product from Salvia prionitis.

Danshenxinkun B has antioxIdant activity, it may have the potential of being used as natural antioxidants in foods and cosmetics.

Tetrahydro tanshinone I is one compound of Fufang Danshen Prescription (FDP) , liposome equilibrium dialysis system could simply and effectively esti-mate the absorption of multiple components in FDP in vivo, and predicts the potential bioactivity of thes

Przewaquinone A has antitumor activity.

Ferruginol has anti-plasmodial, leishmanicidal, anti-ulcerogenic, cardioprotective, anticancer, anti-oxidative and anti-inflammatory activities, it can induce apoptosis in non-small cell lung cancer (NSCLC) cells.

Tilifodiolide exerts in vitro and in vivo anti-inflammatory activity and in vivo antinociceptive effects. Tilifodiolide exerted antidiarrheal activity by decreasing the intestinal fluid accumulation and vasorelaxant effects mediated by nitric oxide and cyclic guanosine monophosphate, it also showed anxiolytic and antidepressant effects by the partial involvement of gamma-Aminobutyric acid (GABA) receptors and the possible participation of α2-adrenoreceptors, respectively.

Isosalvianolic acid B is a natural from Salviae miltiorrhizae

Dehydromiltirone has antioxidant activity, it shows significant anti-neuroinflammatory effects through inhibiting PI3K Akt phosphorylation and then inhibiting NF-κB signaling pathway.

3-Oxosapriparaquinone is a natural product from Salvia prionitis.

12-Hydroxysapriparaquinone is a natural product from Salvia prionitis.

Isotanshinone II, a natural product of Salvia (Lamiaceae), has a catalog number TN4332 and CAS number 98249-39-9, and can be used as a reference standard.

Danshenxinkun A, Danshenxinkun B and Neocryptotanshinone may intervene thrombotic diseases by adjusting the targets mainly involved in pathways of endocrine system, signal transduction, signaling molecules and interaction, cell motility, environmental ada

Salviolone exhibits cytotoxic activity against Vero cells.

Saprirearine is a natural product of Salvia, Lamiaceae. The catalog number is TN4945 and the CAS number is 453518-30-4. Saprirearine can be used as a reference standard.