4-methyl-6-phenyl-2H-pyranone is derived from Scutellaria baicalensis Georgi and improves mitochondrial functionality to protect astrocytes against hydrogen peroxide-induced toxicity.
2-(4-Hydroxyphenyl)-6-methyl-2,3-dihydro-4H-pyran-4-one is a natural product of Scutellaria, Lamiaceae. The catalog number is TN2722 and the CAS number is 1167483-18-2. 2-(4-Hydroxyphenyl)-6-methyl-2,3-dihydro-4H-pyran-4-one can be used as a reference standard.
Scutellaric acid is a natural product of Scutellaria, Lamiaceae. The catalog number is TN4979 and the CAS number is 102919-76-6. Scutellaric acid can be used as a reference standard.
6-O-Nicotinoylscutebarbatine G shows cytotoxic activities against three human tumor cell lines, namely, HONE-1 nasopharyngeal, KB oral epidermoid carcinoma, and HT29 colorectal carcinoma cells, and with IC50 values in the range of 2.1 5.7 μM.
Viscidulin II can be potential therapeutic agents against P. acnes-induced skin inflammation, it can significantly suppress P. acnes-induced IL-8 and IL-1β production in THP-1 cells, concomitant intradermal injection of viscidulin II with P. acnes can effectively attenuate P. acnes-induced ear swelling, and decrease the production of IL-6 and tumor necrosis factor-α in ear homogenates.
2',4'-Dihydroxy-2,3',6'-trimethoxychalcone, a natural product of Scutellaria, Lamiaceae, has a catalog number TN2713 and CAS number 100079-39-8. It can be used as a reference standard.
7-Hydroxy-2',5,8-trimethoxyflavanone is a natural product of Scutellaria, Lamiaceae. The catalog number is TN3227 and the CAS number is 100079-34-3. 7-Hydroxy-2',5,8-trimethoxyflavanone can be used as a reference standard.
Scutebarbatine A shows significant antitumor effects on A549 cells in vivo and in vitro via mitochondria-mediated apoptosis by up-regulating expressions of caspase-3 and 9, and down-regulating Bcl-2. Scutebarbatine A and barbatine A show a significant ability to protect cells against H2O2 with ED50 values of 5.0 and 16.8 μM, respectively.
Scutebarbatine X can inhibit nitric oxide production efficiently with IC50 values of lower than 50 μM, it may have potential effects on the reduction of neuroinflammation.
2-Hydroxy-3-methylanthraquinone enhances apoptosis of U937 cells,in part,through activation of p-p38MAPK and downregulation of p-ERK1/2; triggers caspase-3 activation mediated apoptotic induction.
Skullcapflavone I has anti-inflammatory and anti-allergic potential, it can significantly inhibit LPS stimulated NO and PGE(2) release in J774A.1 macrophages and inhibit LPS induced IL-6 production in a concentration dependent manner. Skullcapflavone I se
Scutebata G is a natural product of Scutellaria, Lamiaceae. The catalog number is TN5573 and the CAS number is 1207181-63-2. Scutebata G can be used as a reference standard.
19-[(beta-D-glucopyranosyl)oxy]-19-oxo-ent-labda-8(17),13-dien-16,15-olide is a natural product for research related to life sciences. The catalog number is TN2661 and the CAS number is 919120-78-8.
2',7-Dihydroxy-5,8-dimethoxyflavanone is a natural product of Scutellaria, Lamiaceae. The catalog number is TN2745 and the CAS number is 1351338-14-1. 2',7-Dihydroxy-5,8-dimethoxyflavanone can be used as a reference standard.
5,2',6'-Trihydroxy-6,7,8-trimethoxyflavone (ED 50 =4.5 ug/ml ) shows cytotoxicity against L1210 cell and has inhibiting effects on ATPase from the cell.
Scutebarbatine W can inhibit nitric oxide production efficiently with IC50 values of lower than 50 μM, it may have potential effects on the reduction of neuroinflammation.
(2S)-2',5,6',7-Tetrahydroxyflavanone can inhibit the lipid peroxide formation induced by adenosine diphosphate and reduced nicotinamide adenine dinucleotide phosphate in rat liver homogenate.