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Scutellaria

  • 5,7-Diacetoxy-8-methoxyflavone
    TN309123246-80-2
    5,7-Diacetoxy-8-methoxyflavone is derived from the roots of Scutellaria baicalensis and inhibits cAMP phosphodiesterase.
    • $112
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  • 4-methyl-6-phenyl-2H-pyranone
    TN24364467-30-5
    4-methyl-6-phenyl-2H-pyranone is derived from Scutellaria baicalensis Georgi and improves mitochondrial functionality to protect astrocytes against hydrogen peroxide-induced toxicity.
    • $50
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  • Viscidulin I
    T393292519-95-4
    Viscidulin I is found in Scutellaria baicalensis and is a natural product.
    • $165
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  • Norwogonin
    T82054443-09-8
    Norwogonin (5,7,8-Trihydroxyflavone), isolated from Scutellaria baicalensis Georgi, possesses antiviral activity against Enterovirus 71 (IC50: 31.83 μg/ml).
    • $68
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  • Malic acid
    T2S08506915-15-7
    1. Malic acid (Pomalus acid) did reduce populations of L. monocytogenes on poultry. 2. Malic acid supplementation may be useful for conservative treatment of calcium renal stone disease by virtue of its capacity to induce these effects.
    • $39
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  • Scutellarin
    T278927740-01-8
    Scutellarin (Scutellarein-7-glucuronide), an active flavone isolated from Scutellaria baicalensis, can inhibit RANKL-mediated MAPK and NF-κB signaling pathway in osteoclasts, and down-regulate the STAT3 Girdin Akt signaling in HCC cells.
    • $45
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  • Baicalein
    T2858491-67-8
    Baicalein (5,6,7-Trihydroxyflavone) is a xanthine oxidase inhibitor.
    • $33
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  • Oroxin B
    T3780114482-86-9
    Oroxin B (Hypocretin-2) has antioxidant activity.
    • $110
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  • Scutellarein
    T3319529-53-3
    Scutellarein (6-Hydroxyapigenin) reduces inflammatory responses by inhibiting Src kinase activity.
    • $110
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  • Baicalin
    T277521967-41-9
    Baicalin (Baicalein 7-O-β-D-glucuronide) is a prolyl endopeptidase inhibitor isolated from scutellaria baicalensis, with antioxidant, anti-tumor, anti-HIV properties.
    • $31
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  • Scutellarein tetramethyl ether
    TN12711168-42-9
    Scutellarein tetramethyl ether (4',5,6,7-Tetramethoxyflavone) is extracted from Siam weeds and exhibits anti-inflammatory activity through NF-κB pathway.
    • $83
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  • Wogonin
    T2933632-85-9
    Wogonin (Vogonin) is a cell-permeable and orally available flavonoid that displays anti-inflammatory and anticancer properties.
    • $50
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  • 2-(4-Hydroxyphenyl)-6-methyl-2,3-dihydro-4H-pyran-4-one
    TN27221167483-18-2
    2-(4-Hydroxyphenyl)-6-methyl-2,3-dihydro-4H-pyran-4-one is a natural product of Scutellaria, Lamiaceae. The catalog number is TN2722 and the CAS number is 1167483-18-2. 2-(4-Hydroxyphenyl)-6-methyl-2,3-dihydro-4H-pyran-4-one can be used as a reference standard.
    • $660
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  • Scutellaric acid
    TN4979102919-76-6
    Scutellaric acid is a natural product of Scutellaria, Lamiaceae. The catalog number is TN4979 and the CAS number is 102919-76-6. Scutellaric acid can be used as a reference standard.
    • $1,980
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  • Rivularin
    TN215770028-59-0
    Rivularin is a natural product
    • $262
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  • Viscidulin II
    TN523892519-93-2
    Viscidulin II can be potential therapeutic agents against P. acnes-induced skin inflammation, it can significantly suppress P. acnes-induced IL-8 and IL-1β production in THP-1 cells, concomitant intradermal injection of viscidulin II with P. acnes can effectively attenuate P. acnes-induced ear swelling, and decrease the production of IL-6 and tumor necrosis factor-α in ear homogenates.
    • $740
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  • 4'-Hydroxywogonin
    TN127657096-02-3
    4'-Hydroxywogonin has positive effect on inhabiting those human tumor lines in vitro, with IC50 value is 8.3-38.4ug/mL .
    • $1,980
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  • Scutebarbatine A
    TN2191176520-13-1
    Scutebarbatine A shows significant antitumor effects on A549 cells in vivo and in vitro via mitochondria-mediated apoptosis by up-regulating expressions of caspase-3 and 9, and down-regulating Bcl-2. Scutebarbatine A and barbatine A show a significant ability to protect cells against H2O2 with ED50 values of 5.0 and 16.8 μM, respectively.
    • $1,520
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  • Dihydrooroxylin A
    TN385618956-18-8
    Dihydrooroxylin A has significant antifeeding activity.
    • $710
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  • Scutebata F
    TN49771207181-62-1
    Scutebata F is a natural product for research related to life sciences. The catalog number is TN4977 and the CAS number is 1207181-62-1.
    • $2,210
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  • Skullcapflavone I
    TN503341060-16-6
    Skullcapflavone I has anti-inflammatory and anti-allergic potential, it can significantly inhibit LPS stimulated NO and PGE(2) release in J774A.1 macrophages and inhibit LPS induced IL-6 production in a concentration dependent manner. Skullcapflavone I se
    • $460
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  • 2-Hydroxy-3-methylanthraquinone
    TN121117241-40-6
    2-Hydroxy-3-methylanthraquinone enhances apoptosis of U937 cells,in part,through activation of p-p38MAPK and downregulation of p-ERK1/2; triggers caspase-3 activation mediated apoptotic induction.
    • $550
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  • Scutebata C
    TN49751207181-59-6
    Scutebata B possesses a rare alpha-hydroxy group in its alpha,beta-unsaturated lactone rings.
    • $2,435
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  • 6-O-Nicotinoylbarbatin C
    TN13231015776-92-7
    6-O-Nicotinoylbarbatin C is a natural product
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  • 2',5,6',7-Tetraacetoxyflavanone
    TN272480604-17-7
    2',5,6',7-Tetraacetoxyflavanone is a natural product for research related to life sciences. The catalog number is TN2724 and the CAS number is 80604-17-7.
    • $550
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  • Scutebata G
    TN55731207181-63-2
    Scutebata G is a natural product of Scutellaria, Lamiaceae. The catalog number is TN5573 and the CAS number is 1207181-63-2. Scutebata G can be used as a reference standard.
    • $750
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  • 8,8''-Bibaicalein
    TN3268135309-02-3
    8,8''-Bibaicalein is a natural product from Scutellaria baicalensis.
    • $710
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  • 5,7,4'-Trihydroxy-8-methylflavanone
    TN1288916917-28-7
    5,7,4'-Trihydroxy-8-methylflavanone is a natural product
    • $290
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  • Scutebata B
    TN49741207181-58-5
    Scutebata B inhibited NO production efficiently with IC50 values of lower than 50 μM.
    • $820
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  • Baicalin methyl ester
    TN142782475-03-4
    Baicalin methyl ester shows inhibitory effects on the Avian Myeloblastosis Virus reverse transcriptase (AMV-RT).
    • $50
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  • Viscidulin III tetraacetate
    TN523996684-81-0
    Viscidulin III tetraacetate is a natural product for research related to life sciences. The catalog number is TN5239 and the CAS number is 96684-81-0.
    • $620
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  • Apigenin 5-O-beta-D-glucopyranoside
    TN343128757-27-9
    Apigenin 5-O-beta-D-glucopyranoside has inhibitory activity against the enzyme yeast a-glucosidase, withthe IC50 value of 287.12 muM.
      7-10 days
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    • 6-O-Nicotinoylscutebarbatine G
      TN13241206805-30-2
      6-O-Nicotinoylscutebarbatine G shows cytotoxic activities against three human tumor cell lines, namely, HONE-1 nasopharyngeal, KB oral epidermoid carcinoma, and HT29 colorectal carcinoma cells, and with IC50 values in the range of 2.1 5.7 μM.
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    • Plantagoside
      TJS085178708-33-5
      Plantagoside is a specific non-competitive inhibitor for jack bean alpha-mannosidase (IC50: 5 μM). It also is a potent inhibitor of the Maillard reaction.
      • $72
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    • Oroxin A
      T5S078857396-78-8
      Oroxin A (Baicalein 7-O-glucoside) has antitussive and expectorant effects.
      • $36
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    • Oroxylin A-7-O-glucuronide
      T389136948-76-2
      Oroxylin A-7-O-glucuronide (Oroxylin A Glucoronide) and wogonoside should also be served as the chemical markers together with baicalin for the quality control of herbs and proprietary traditional Chinese medicine (PTCM) products of radix Scutellariae. Oroxylin A 7-O-glucuronide, Oroxin A, and Oroxin B can bind to the stem region of α-hemolysin (α-HL), when inhibiting the hemolytic activity of α-HL. Oroxylin A 7-O-glucuronide and 4', 5, 7-trihydroxy-6-methoxyflavone at a concentration of 100 microM inhibit 34 and 43% of total prolyl oligopeptidase (POP) activity, respectively.
      • $80
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    • Scutebarbatine Z
      TN21961312716-28-1
      Scutebarbatine Z is a natural product from Scutellaria barbata.
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    • Negletein
      T2S084329550-13-8
      1. Negletein (7-O-Methylbaicalein) has anti-inflammatory and immunomodulatory activities via inhibition of TNF-α, iNOS and IL-1β. 2. Negletein as a neuroprotectant enhances the action of nerve growth factor and induces neurite outgrowth in PC12 cells. 3. Negletein shows a comparable redox-active potential, and it (50 μM, 4 h) can activate Nrf2. 4. Negletein shows significant antimicrobial activity. 5. Negletein has anti-hypoxia activity, it can significantly prolong the survival time of hypoxic mice.6. Negletein has anti- Alzheimer's disease activity, it inhibits the iron-dependent formation of ROS and also blocks the iron-induced oligomerization of amyloid beta 42 in vitro. 7. Negletein (IC50: 3.89 +/- 0.39 microM) exhibits potent inhibitory activity against nuclear factor of activated T cells (NFAT) transcription factor.
      • $128
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    • 5,6,7-TRIMETHOXYFLAVONE
      T7051973-67-1
      5,6,7-Trimethoxyflavone, a natural product extracted from Japanese Callicarpa, acts as a p38-α MAPK inhibitor and exhibits anti-inflammatory properties.
      • $34
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    • 2',4'-Dihydroxy-2,3',6'-trimethoxychalcone
      TN2713100079-39-8
      2',4'-Dihydroxy-2,3',6'-trimethoxychalcone is a natural product of Scutellaria, Lamiaceae. The catalog number is TN2713 and the CAS number is 100079-39-8. 2',4'-Dihydroxy-2,3',6'-trimethoxychalcone can be used as a reference standard.
      • $670
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    • Skullcapflavone II
      TN104055084-08-7
      Skullcapflavone II is a flavonoid derived from Scutellaria baicalensis, a widely used herbal medicine in anti-inflammatory and anticancer therapy. Skullcapflavone II may have therapeutic potential for the treatment of allergic asthma.Skullcapflavone II regulates osteoclast differentiation, survival, and function. Skullcapflavone II exerts potent antimicrobial activity against M. aurum and M. bovis BCG
      • $98
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    • Scutebarbatine B
      TN2192905929-95-5
      Scutebarbatine B shows weak cytotoxicity with IC50 values ranging from 35.11 to 42.73 μM against K562 cell lines and HL60 cell lines.
      • $2,178
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    • Scutebarbatine X
      TN21941312716-26-9
      Scutebarbatine X can inhibit nitric oxide production efficiently with IC50 values of lower than 50 μM, it may have potential effects on the reduction of neuroinflammation.
      • $2,178
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    • 7-Hydroxy-2',5,8-trimethoxyflavanone
      TN3227100079-34-3
      7-Hydroxy-2',5,8-trimethoxyflavanone is a natural product of Scutellaria, Lamiaceae. The catalog number is TN3227 and the CAS number is 100079-34-3. 7-Hydroxy-2',5,8-trimethoxyflavanone can be used as a reference standard.
      • $620
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    • Scutebata E
      TN49761207181-61-0
      Scutebata E shows weak cytotoxicity with IC50 values ranging from 35.11 to 42.73 μM against K562 cell lines.
      • $740
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    • Naringenin 7,4'-diacetate
      TN544218196-13-9
      Naringenin 7,4'-diacetate is a natural product for research related to life sciences. The catalog number is TN5442 and the CAS number is 18196-13-9.
      • $360
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    • Scutellarin methyl ester
      T2S0842119262-68-9
      Scutellarin methyl ester has the effect of improving sleep, such as prolonging sleep time, increasing the incidence of sleep, shortening sleep latency, which also helps to delay aging process.
      • $100
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    • Baicalein 7-O-beta-D-ethylglucuronide
      TN3480675624-38-1
      Baicalein 7-O-beta-D-ethylglucuronide is a natural product from Scutellaria baicalensis Georgi.
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    • Ombuoside
      TN201120188-85-6
      Ombuoside (Ombuin-3beta-rutinoside) has antifungal activity. Ombuoside shows significant antioxidant activity in the DPPH, and TEAC, reducing power assays.Ombuoside is a glycoside ombuoside isolated from Gynostemma pentaphyllum.
      • $64
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    • 5,​7,​4'-​Trimethoxyflavone
      T82965631-70-9
      5,7,4'-Trimethoxyflavone (4',5,7-Trimethoxyflavone) is isolated from Kaempferia parviflora (KP) which is a medicinal plant from Thailand.
      • $41
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