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SF 11

Catalog No. T23349Cas No. 443292-81-7

SF 11 is a potent, brain-penetrant neuropeptide Y Y2 receptor antagonist with an IC50 of 199 nM, exhibiting antidepressant-like activity.

SF 11

SF 11

Purity: 98.54%
Catalog No. T23349Cas No. 443292-81-7
SF 11 is a potent, brain-penetrant neuropeptide Y Y2 receptor antagonist with an IC50 of 199 nM, exhibiting antidepressant-like activity.
Pack SizePriceAvailabilityQuantity
1 mg$29In Stock
2 mg$44In Stock
5 mg$73In Stock
10 mg$118In Stock
25 mg$238In Stock
50 mg$418In Stock
100 mg$648In Stock
200 mg$870In Stock
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Purity:98.54%
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Product Introduction

Bioactivity
Description
SF 11 is a potent, brain-penetrant neuropeptide Y Y2 receptor antagonist with an IC50 of 199 nM, exhibiting antidepressant-like activity.
Targets&IC50
NPYY2 receptor:199 nM (IC50)
Chemical Properties
Molecular Weight446.6
FormulaC27H30N2O2S
Cas No.443292-81-7
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
Ethanol: < 22.33 mg/mL
DMSO: 40 mg/mL (89.57 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.2391 mL11.1957 mL22.3914 mL111.9570 mL
5 mM0.4478 mL2.2391 mL4.4783 mL22.3914 mL
10 mM0.2239 mL1.1196 mL2.2391 mL11.1957 mL
20 mM0.1120 mL0.5598 mL1.1196 mL5.5979 mL
50 mM0.0448 mL0.2239 mL0.4478 mL2.2391 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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