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Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $1,520 | 8-10 weeks | |
50 mg | $1,980 | 8-10 weeks | |
100 mg | $2,500 | 8-10 weeks |
Description | SJ1461 is a potent, orally active inhibitor of the BET family, selectively targeting and inhibiting BRD2 (BD1), BRD2 (BD2), BRD4 (BD1), and BRD4 (BD2) with respective IC50 values of 1.6 nM, 0.1 nM, 6.5 nM, and 0.2 nM [1]. |
In vitro | SJ1461 inhibits the growth of cancer cells in MV4-11, NALM-16, MOLM-13, HDMB03, and D283 lines, with respective IC50 values of 20 nM, 3.6 nM, 10.2 nM, 6.6 nM, and 56.2 nM [1]. |
Molecular Weight | 484 |
Formula | C21H18ClN7OS2 |
Cas No. | 2924546-70-1 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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