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Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $1,520 | 1-2 weeks | |
50 mg | $1,980 | 1-2 weeks | |
100 mg | $2,500 | 1-2 weeks |
Description | Talotrexin (PT523), an analog of Aminopterin, is a nonpolyglutamatable classic antifolate that specifically inhibits the reduced folate carrier (RFC), selectively impeding RFC transport and targeting dihydrofolate reductase (DHFR) to demonstrate antitumor activity and inhibit tumor growth [1] [2]. |
Alias | PT523 |
Molecular Weight | 573.56 |
Formula | C27H27N9O6 |
Cas No. | 113857-87-7 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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