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Results for "
talotrexin
" in TargetMol Product Catalog- Inhibitors & Agonists2
Talotrexin
PT523
T73085113857-87-7
Talotrexin (PT523), an analog of Aminopterin, is a nonpolyglutamatable classic antifolate that specifically inhibits the reduced folate carrier (RFC), selectively impeding RFC transport and targeting dihydrofolate reductase (DHFR) to demonstrate antitumor activity and inhibit tumor growth [1] [2].
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Talotrexin ammonium
T64295648420-92-2In house
Talotrexin ammonium is a non-polyglutamic acid antifolate. Talotrexin ammonium inhibits tumor growth by targeting dihydrofolate reductase (DHFR), thereby improving anti-tumor activity in a wide range of cancer models, helping to inhibit tumor growth.
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