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Taquidil
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Catalog No. T13177Cas No. 71395-14-7
Tocainide hydrochloride, a sodium channel blocker, inhibits the sodium channels in the pain-producing foci in nerve membranes. It is an orally effective antiarrhythmic agent, structurally and pharmacologically similar to lidocaine [1][2].
Taquidil
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Catalog No. T13177Cas No. 71395-14-7
Tocainide hydrochloride, a sodium channel blocker, inhibits the sodium channels in the pain-producing foci in nerve membranes. It is an orally effective antiarrhythmic agent, structurally and pharmacologically similar to lidocaine [1][2].
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 2 mg | $52 | 5 days | |
| 1 mL x 10 mM (in DMSO) | $98 | 5 days |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Tocainide hydrochloride, a sodium channel blocker, inhibits the sodium channels in the pain-producing foci in nerve membranes. It is an orally effective antiarrhythmic agent, structurally and pharmacologically similar to lidocaine [1][2]. |
| Targets&IC50 | Na+ channel: |
| In vivo | Tocainide (100 mg/kg) effectively reduces ventricular ectopic activity in unanesthetized dogs with coronary occlusion. Cessation of tocainide in models of digitalis toxicity and coronary occlusion rapidly causes a resurgence of ventricular ectopic activity [1]. |
| Molecular Weight | 228.718 |
| Formula | C11H17ClN2O |
| Cas No. | 71395-14-7 |
| Relative Density. | 1.31g/cm3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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