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Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $1,860 | 10-14 weeks | |
50 mg | $2,524 | 10-14 weeks |
Description | TAS-117 hydrochloride is a selective, potent, orally active allosteric Akt inhibitor, acting on Akt1 (IC50: 4.8 nM), Akt2 (IC50: 1.6 nM) and Akt3 (IC50: 44 nM). TAS-117 hydrochloride stimulates anti-myeloma activity, enhances lethal endoplasmic reticulum stress induced by proteasome inhibition, and can induce apoptosis and autophagy. |
Molecular Weight | 460.96 |
Formula | C26H25ClN4O2 |
Cas No. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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