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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $793 | 35 days |
Description | TASP 0277308 is a potent and selective sphingosine 1-phosphate 1 (S1P1) receptor antagonist (IC50 = 7.8 nM). TASP 0277308 inhibits S1P-induced chemotaxis (IC50 = 1.1-1.6 nM), HUVEC cell proliferation (IC50 = 3-3.6 nM) and suppresses angiogenesisin vivo. TASP 0277308 also blocks VEGF-induced tube-formation of HUVECsin vitroand reverses or impairs the development of arthritis or mechano-allodynia. |
Molecular Weight | 539.48 |
Formula | C23H28Cl2N6O3S |
Cas No. | 945725-50-8 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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