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Tazanolast

Name: Tazanolast
Brand: TargetMol
SKU: T17001
Price: 44 USD
Availability: InStock
Rating: 4.5 (1 reviews)

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Catalog No. T17001Cas No. 82989-25-1

Alias TO 188, Tazanol, Tazalest

Tazanolast, a selective mast-cell-stabilizing drug, inhibits the release of chemical mediators (histamine and leukotrienes) from mast cells, reduces inflammation, and is used in the treatment of allergic disorders, such as asthma and allergic rhinitis.

Tazanolast

😃Good

Catalog No. T17001Alias TO 188, Tazanol, TazalestCas No. 82989-25-1

Pack Size	Price	Availability
25 mg	1.444 €	6-8 weeks
50 mg	1.881 €	6-8 weeks
100 mg	2.375 €	6-8 weeks

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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity

Description	Tazanolast, a selective mast-cell-stabilizing drug, inhibits the release of chemical mediators (histamine and leukotrienes) from mast cells, reduces inflammation, and is used in the treatment of allergic disorders, such as asthma and allergic rhinitis.
In vitro	Tazanolast has been shown to suppress passive cutaneous anaphylaxis, Schultz-Dale reaction in isolated tracheal muscle, and experimental asthma without antagonistic actions upon histamine- and leukotriene-D4-induced contraction [1].
In vivo	Pre-administration of Tazanolast at doses of 30, 100, or 300 mg/kg inhibits ozone-induced airway hyperresponsiveness in a dose-dependent manner, showing significant efficacy in guinea pigs [1].
Alias	TO 188, Tazanol, Tazalest

Chemical Properties

Molecular Weight	289.29
Formula	C₁₃H₁₅N₅O₃
Cas No.	82989-25-1
Relative Density.	1.343 g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

TO-188TO188Tazanolast