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TC113

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Catalog No. T74400

TC113, a Gemcitabine (GEM)-based conjugate incorporating the c(RGDyK) sequence, is internalized by A549 cells via the integrin αvβ3 pathway. It demonstrates significant antiproliferative effects on both WM266.4 and A549 cell lines.

TC113

TC113

😃Good
Catalog No. T74400
TC113, a Gemcitabine (GEM)-based conjugate incorporating the c(RGDyK) sequence, is internalized by A549 cells via the integrin αvβ3 pathway. It demonstrates significant antiproliferative effects on both WM266.4 and A549 cell lines.
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Product Introduction

Bioactivity
Description
TC113, a Gemcitabine (GEM)-based conjugate incorporating the c(RGDyK) sequence, is internalized by A549 cells via the integrin αvβ3 pathway. It demonstrates significant antiproliferative effects on both WM266.4 and A549 cell lines.
Chemical Properties
Molecular Weight908.86
FormulaC37H50F2N12O13
Storage & Solubility Information
StorageShipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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