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tCFA15

tCFA15
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tCFA15

Catalog No. T13917Cas No. 220757-88-0
tCFA15, a trimethyl cyclohexenonic long-chain fatty alcohol with a 15-carbon atom side chain, may regulate Notch signaling and promote neuronal differentiation.
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Pack SizePriceAvailabilityQuantity
5 mg$3156-8 weeks
25 mg$9876-8 weeks
50 mg$1,3606-8 weeks
100 mg$1,9906-8 weeks
1 mL x 10 mM (in DMSO)$3186-8 weeks
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Product Introduction

Bioactivity
Description
tCFA15, a trimethyl cyclohexenonic long-chain fatty alcohol with a 15-carbon atom side chain, may regulate Notch signaling and promote neuronal differentiation.
In vitro
tCFA15 (10 nM-1μM) dose-dependently promotes the differentiation of neural stem cell-derived neurospheres by promoting neurons at the expense of astrocytes, and this effect is through Notch1. tCFA15 (1 μM) specifically decreases the level of Notch1 mRNA in spheres, and such an effect is also observed in decreases Notch1 expression in neuronal and glial cell cultures[1]. tCFA15 stimulates arginine vasopressin secretion in nerve terminals of the neurohypophysis[2].
Chemical Properties
Molecular Weight364.61
FormulaC24H44O2
Cas No.220757-88-0
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 130 mg/mL (356.56 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.7427 mL13.7133 mL27.4266 mL137.1328 mL
5 mM0.5485 mL2.7427 mL5.4853 mL27.4266 mL
10 mM0.2743 mL1.3713 mL2.7427 mL13.7133 mL
20 mM0.1371 mL0.6857 mL1.3713 mL6.8566 mL
50 mM0.0549 mL0.2743 mL0.5485 mL2.7427 mL
100 mM0.0274 mL0.1371 mL0.2743 mL1.3713 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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