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Tessaric acid

Catalog No. TN6511Cas No. 58142-10-2

Tessaric acid has antifeedant and allelochemical effects. Tessaric acid derivatives induce G/M cell cycle arrest in human solid tumor cell lines.

Tessaric acid

Tessaric acid

Catalog No. TN6511Cas No. 58142-10-2
Tessaric acid has antifeedant and allelochemical effects. Tessaric acid derivatives induce G/M cell cycle arrest in human solid tumor cell lines.
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5 mg$510Backorder
1 mL x 10 mM (in DMSO)$520Backorder
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Product Introduction

Bioactivity
Description
Tessaric acid has antifeedant and allelochemical effects. Tessaric acid derivatives induce G/M cell cycle arrest in human solid tumor cell lines.
In vitro
METHODS AND RESULTS:A series of analogs were synthesized in a straightforward manner from naturally available sesquiterpenes ilicic acid and Tessaric acid. The in vitro antiproliferative activities were examined in the human solid tumor cell lines A2780, HBL-100, HeLa, SW1573, T-47D and WiDr. The most potent analog induced considerably growth inhibition in the range 1.9-4.5 microM. CONCLUSIONS: Cell cycle studies for Tessaric acid derivatives indicated a prominent arrest of the cell cycle at the G(2)/M phase. Damage to the cells was permanent as determine by the so called 24+24 drug schedule.
Chemical Properties
Molecular Weight248.32
FormulaC15H20O3
Cas No.58142-10-2
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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