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TG-2-IN-1

🥰Excellent
Catalog No. T60274Cas No. 135273-74-4

TG-2-IN-1 is a potent transglutaminase-2 (TGM-2) inhibitor.TG-2-IN-1 is used in the study of cancer, neurological disorders, and immune system disorders.

TG-2-IN-1

TG-2-IN-1

🥰Excellent
Catalog No. T60274Cas No. 135273-74-4
TG-2-IN-1 is a potent transglutaminase-2 (TGM-2) inhibitor.TG-2-IN-1 is used in the study of cancer, neurological disorders, and immune system disorders.
Pack SizePriceAvailabilityQuantity
1 mg$41In Stock
5 mg$89In Stock
10 mg$128In Stock
25 mg$212In Stock
50 mg$312In Stock
100 mg$463In Stock
500 mg$1,070In Stock
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Product Introduction

Bioactivity
Description
TG-2-IN-1 is a potent transglutaminase-2 (TGM-2) inhibitor.TG-2-IN-1 is used in the study of cancer, neurological disorders, and immune system disorders.
Chemical Properties
Molecular Weight220.72
FormulaC8H13ClN2OS
Cas No.135273-74-4
Smiles[Cl-].O=C(C)CSC=1N(C=C[N+]1C)C
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: 80 mg/mL (362.45 mM), Sonication is recommended.
DMSO: 20 mg/mL (90.61 mM), Sonication is recommended.
Solution Preparation Table
DMSO/H2O
1mg5mg10mg50mg
1 mM4.5306 mL22.6531 mL45.3063 mL226.5314 mL
5 mM0.9061 mL4.5306 mL9.0613 mL45.3063 mL
10 mM0.4531 mL2.2653 mL4.5306 mL22.6531 mL
20 mM0.2265 mL1.1327 mL2.2653 mL11.3266 mL
50 mM0.0906 mL0.4531 mL0.9061 mL4.5306 mL
H2O
1mg5mg10mg50mg
100 mM0.0453 mL0.2265 mL0.4531 mL2.2653 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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%
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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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