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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Thiol-PEG5-alcohol, a PEG-based linker for PROTACs, connects two essential ligands crucial for PROTAC molecule formation and facilitates selective protein degradation via the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two ligands linked by a connector: one binds to an E3 ubiquitin ligase and the other to the target protein. They leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Alias | HS-PEG5-OH |
Molecular Weight | 254.34 |
Formula | C10H22O5S |
Cas No. | 248582-03-8 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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