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TOK-8801
TOK-8801 is a synthetic dihydroimidazole thiazole carboxamide with immunomodulatory activity that eliminates the stimulatory effects of antibody production by removing T cells.CAS 번호128-63-63-5
Catalog No. T13180Cas No. 105963-46-0
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Purity:99.25%
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TOK-8801
Catalog No. T13180Cas No. 105963-46-0
TOK-8801 is a synthetic dihydroimidazole thiazole carboxamide with immunomodulatory activity that eliminates the stimulatory effects of antibody production by removing T cells.CAS 번호128-63-63-5
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $293 | In Stock | |
| 5 mg | $722 | In Stock | |
| 10 mg | $987 | In Stock | |
| 25 mg | $1,520 | In Stock | |
| 50 mg | $1,980 | In Stock | |
| 100 mg | $2,500 | In Stock |
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Chemical Properties
| Description | TOK-8801 is a synthetic dihydroimidazole thiazole carboxamide with immunomodulatory activity that eliminates the stimulatory effects of antibody production by removing T cells.CAS 번호128-63-63-5 |
| In vitro | TOK-8801 enhanced the anti-sheep red blood cells (SRBC) plaque forming cells (PFC) response and mitogen-induced proliferative responses in murine splenocytes and thymocytes in vitro at concentrations of 10(-7)-10(-5) M, while LMS augmented these responses at 10(-4) M[1]. |
| In vivo | TOK-8801 (0.5 mg/kg, p.o.) suppressed the production of anti-SRBC PFC in normal mice, but restored the inhibition of antibody production in restraint stress mice[1]. |
| Molecular Weight | 315.43 |
| Formula | C17H21N3OS |
| Cas No. | 105963-46-0 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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