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Tos-PEG4-NH-Boc

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Catalog No. T18628Cas No. 1246999-33-6
Alias PROTAC Linker 7

Tos-PEG4-NH-Boc (PROTAC Linker 7) is a PEG-based linker utilized in the synthesis of PROTACs[1].

Tos-PEG4-NH-Boc

Tos-PEG4-NH-Boc

😃Good
Catalog No. T18628Alias PROTAC Linker 7Cas No. 1246999-33-6
Tos-PEG4-NH-Boc (PROTAC Linker 7) is a PEG-based linker utilized in the synthesis of PROTACs[1].
Pack SizePriceAvailabilityQuantity
100 mgInquiry7-10 days
500 mgInquiry7-10 days
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Product Introduction

Bioactivity
Description
Tos-PEG4-NH-Boc (PROTAC Linker 7) is a PEG-based linker utilized in the synthesis of PROTACs[1].
In vitro
PROTACs consist of two ligands joined by a linker: one ligand binds to an E3 ubiquitin ligase, and the other targets the specific protein. By leveraging the intracellular ubiquitin-proteasome system, PROTACs selectively degrade target proteins[1].
AliasPROTAC Linker 7
Chemical Properties
Molecular Weight447.54
FormulaC20H33NO8S
Cas No.1246999-33-6
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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2 Enter the in vivo formulation:
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Keywords

Tos-PEG-4-NH-BocTos-PEG4-NH-BocTosPEG4NHBocTos PEG4 NH Boc
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