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V-0219

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Catalog No. T60047Cas No. 878453-71-5

V-0219 is a positive allosteric modulator of GLP-1 and can be used in studies about obesity-associated diabetes.

V-0219

V-0219

😃Good
Catalog No. T60047Cas No. 878453-71-5
V-0219 is a positive allosteric modulator of GLP-1 and can be used in studies about obesity-associated diabetes.
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2 mg107 €5 days
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Product Introduction

Bioactivity
Description
V-0219 is a positive allosteric modulator of GLP-1 and can be used in studies about obesity-associated diabetes.
Chemical Properties
Molecular Weight410.43
FormulaC20H25F3N4O2
Cas No.878453-71-5
Relative Density.1.258 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 120 mg/mL (292.38 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.4365 mL12.1823 mL24.3647 mL121.8235 mL
5 mM0.4873 mL2.4365 mL4.8729 mL24.3647 mL
10 mM0.2436 mL1.2182 mL2.4365 mL12.1823 mL
20 mM0.1218 mL0.6091 mL1.2182 mL6.0912 mL
50 mM0.0487 mL0.2436 mL0.4873 mL2.4365 mL
100 mM0.0244 mL0.1218 mL0.2436 mL1.2182 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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