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Vazegepant

Vazegepant
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Vazegepant

Catalog No. T38734Cas No. 1337918-83-8
Vazegepant (Zavegepant) is an orally available and selective antagonist of the calcitonin gene-related peptide CGRP receptor for pain relief and may be used in the study of migraine.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
1 mg$397In Stock
2 mg$595In Stock
5 mg$970In Stock
10 mg$1,290In Stock
25 mg$1,950In Stock
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Product Introduction

Bioactivity
Description
Vazegepant (Zavegepant) is an orally available and selective antagonist of the calcitonin gene-related peptide CGRP receptor for pain relief and may be used in the study of migraine.
AliasZavegepant, BHV-3500, BMS-742413
Chemical Properties
Molecular Weight638.80
FormulaC36H46N8O3
Cas No.1337918-83-8
Storage & Solubility Information
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 30 mg/mL (46.96 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.5654 mL7.8272 mL15.6544 mL78.2718 mL
5 mM0.3131 mL1.5654 mL3.1309 mL15.6544 mL
10 mM0.1565 mL0.7827 mL1.5654 mL7.8272 mL
20 mM0.0783 mL0.3914 mL0.7827 mL3.9136 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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