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Xanthohumol D

Name: Xanthohumol D
Brand: TargetMol
SKU: TN2314
Rating: 4.5 (1 reviews)

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Catalog No. TN2314Cas No. 274675-25-1

Xanthohumol and xanthohumol D are potent inducers of quinone reductase, suggests that they could be used as chemoprevention agents.

Xanthohumol D

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Catalog No. TN2314Cas No. 274675-25-1

Xanthohumol and xanthohumol D are potent inducers of quinone reductase, suggests that they could be used as chemoprevention agents.

Pack Size	Price	Availability	Quantity
1 mg	$249	Backorder
5 mg	Inquiry	Backorder

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Product Introduction

Bioactivity

Description	Xanthohumol and xanthohumol D are potent inducers of quinone reductase, suggests that they could be used as chemoprevention agents.
Targets&IC50	QR2:110 μM (IC50)
In vitro	Six metabolites were obtained as a result of transformation of xanthohumol (1) by selected fungal cultures. Their structures were established on the basis of their spectral data. One of them: 2'-(2'''-hydroxyisopropyl)-dihydrofurano-[4',5':3',4']-4',2-dihydroxy-6'-methoxy-α±,β-dihydrochalcone (6) has not been previously reported in the literature. The antioxidant properties of hops flavonoids and Xanthohumol Derivatives were investigated using the 2,2'-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging method. The effects of these compounds on proliferation of MCF-7, PC-3 and HT-29 human cancer cell lines were determined by the SRB assay.

Chemical Properties

Molecular Weight	370.4
Formula	C₂₁H₂₂O₆
Cas No.	274675-25-1
Relative Density.	1.303 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

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Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

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Keywords

Xanthohumol DNO Synthase