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Br-PEG6-C2-acid, a PEG-based linker for PROTACs, connects two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Br-PEG6-C2-acid, a PEG-based linker for PROTACs, connects two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells. |
In vitro | PROTACs utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins by containing two ligands connected by a linker; one ligand is for an E3 ubiquitin ligase, and the other is for the target protein[1]. |
Alias | Br-PEG6-C2-acid |
Molecular Weight | 417.293 |
Formula | C15H29BrO8 |
Cas No. | 309916-91-4 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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