CD48 Protein, Mouse, Recombinant (His)

Catalog No. TMPY-01372

CD48 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23.7 kDa and the accession number is P18181.

CD48 Protein, Mouse, Recombinant (His)

Catalog No. TMPY-01372

CD48 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23.7 kDa and the accession number is P18181.

Pack Size	Price	Availability	Quantity
100 μg	$600	7-10 days
1 mg	$3,910	7-10 days

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Product Information

Biological Activity	1. Measured by its ability to bind human 2B4 in a functional ELISA. 2. Measured by its ability to bind biotinylated recombinant mouse CD2 in a functional ELISA.
Description	CD48 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23.7 kDa and the accession number is P18181.
Species	Mouse
Expression System	HEK293 Cells
Tag	C-His
Accession Number	P18181
Synonyms	SLAMF2,Sgp-60,MEM-102,CD48 molecule,BLAST-1,BLAST1,BLAST,Bcm-1,BCM1,AW610730,AI449234
Construction	A DNA sequence encoding the mouse CD48 (NP_031675.1) without the propeptide, corresponding to the amino acids (Met 1-Arg 216) was expressed with a C-terminal polyhistidine tag. Predicted N terminal: Phe 23
Protein Purity	> 85 % as determined by SDS-PAGE
Molecular Weight	23.7 kDa (predicted); 45-60 kDa (reducing condition, due to glycosylation)
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice.
Research Background	Cluster of Differentiation 48 (CD48), also known as SLAMF2, BCM-1 and BLAST-1, is a GPI-linked protein belonging to the CD2 subfamily of immunoglobulin superfamily molecules. CD2 and 2B4 (CD244) are known ligands for CD48. CD48 protein is expressed on most lineage-committed hematopoietic cells but not on hematopoietic stem cells or multipotent hematopoietic progenitors. CD48 protein performs biological functions in a variety processes including adhesion, pathogen recognition, cellular activation, and cytokine regulation, and emerges as a critical effector molecule in immune responses.Cancer ImmunotherapyCo-inhibitory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: ICC AntibodiesImmune Checkpoint Detection: IHC AntibodiesImmune Checkpoint Detection: IP AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy