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CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (His), FITC-Labeled

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CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (His), FITC-Labeled

Catalog No. TMPK-01005

CLEC12A has recently been identified as an antigen, expressed on leukemic stem cells and leukemic blasts. Given the fact that this expression profile seems stable throughout diagnosis, treatment and relapse on leukemic blasts and leukemic stem cells, CLEC12A can be considered a highly potent and reliable marker for the detection of measurable residual disease and therefore applicable for risk stratification and prognostication in AML. CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (His), FITC-Labeled is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 24.6 kDa and the accession number is Q5QGZ9-2.

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Pack Size	Price	Availability
100 μg	$1,400	7-10 days
500 μg	$3,720	7-10 days
1 mg	$6,210	7-10 days

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Biological Description

Description	CLEC12A has recently been identified as an antigen, expressed on leukemic stem cells and leukemic blasts. Given the fact that this expression profile seems stable throughout diagnosis, treatment and relapse on leukemic blasts and leukemic stem cells, CLEC12A can be considered a highly potent and reliable marker for the detection of measurable residual disease and therefore applicable for risk stratification and prognostication in AML. CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (His), FITC-Labeled is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 24.6 kDa and the accession number is Q5QGZ9-2.
Species	Human
Expression System	HEK293 Cells
Tag	N-His
Accession Number	Q5QGZ9-2
Synonyms	DCAL-2,HECL,CLL-1,CLECSF7,CD371,CLEC12A,PRO34150,MICL,CLECSF11,CD303,DLEC,DCAL2,CLL1
Construction	His65-Ala265
Protein Purity	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Molecular Weight	24.6 kDa (predicted). Due to glycosylation, the protein migrates to 35-55 kDa based on Tris-Bis PAGE result.
Endotoxin	< 1 EU/μg by the LAL method.
Formulation	Supplied as 0.22 μm filtered solution in PBS (pH 7.4).
Stability & Storage	It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
Research Background	CLEC12A has recently been identified as an antigen, expressed on leukemic stem cells and leukemic blasts. Given the fact that this expression profile seems stable throughout diagnosis, treatment and relapse on leukemic blasts and leukemic stem cells, CLEC12A can be considered a highly potent and reliable marker for the detection of measurable residual disease and therefore applicable for risk stratification and prognostication in AML.

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Keywords

CD-371 PRO 34150 CD 371 DCAL 2 CLL 1 CD-303 CLECSF-7 CLECSF 11 CLECSF-11 CD 303 CLECSF 7 PRO-34150