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(1S,3R,5R)-PIM447 dihydrochloride

Catalog No. T63550

(1S,3R,5R)-PIM447 (dihydrochloride) is a PIM inhibitor with IC50 values of 0.095 μM for Pim1, 0.522 μM for Pim2, and 0.369 μM for Pim3.

(1S,3R,5R)-PIM447 dihydrochloride
Other Forms of (1S,3R,5R)-PIM447 dihydrochloride:
PIM447T124751210608-43-7
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PIM-447 dihydrochlorideT124731820565-69-2
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(1S,3R,5R)-PIM447 dihydrochlorideT13425
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(1S,3R,5R)-PIM447 dihydrochloride

Catalog No. T63550
(1S,3R,5R)-PIM447 (dihydrochloride) is a PIM inhibitor with IC50 values of 0.095 μM for Pim1, 0.522 μM for Pim2, and 0.369 μM for Pim3.
Pack SizePriceAvailabilityQuantity
25 mg$1,35010-14 weeks
50 mg$1,76010-14 weeks
100 mg$2,68010-14 weeks
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Product Introduction

Bioactivity
Description
(1S,3R,5R)-PIM447 (dihydrochloride) is a PIM inhibitor with IC50 values of 0.095 μM for Pim1, 0.522 μM for Pim2, and 0.369 μM for Pim3.
Chemical Properties
Molecular Weight513.38
FormulaC24H25Cl2F3N4O
Storage & Solubility Information
StorageShipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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