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(S)-MCPG

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Catalog No. T13452Cas No. 150145-89-4
Alias (+)-MCPG

(S)-MCPG ((+)-MCPG) is a class I/II metabotropic glutamate receptors (mGluRs) antagonist that blocks spatial learning and long-term enhancement of the dentate gyrus in vivo in rats, and can be used to study neurological disorders.

(S)-MCPG

(S)-MCPG

🥰Excellent
Purity: 98.72%
Catalog No. T13452Alias (+)-MCPGCas No. 150145-89-4
(S)-MCPG ((+)-MCPG) is a class I/II metabotropic glutamate receptors (mGluRs) antagonist that blocks spatial learning and long-term enhancement of the dentate gyrus in vivo in rats, and can be used to study neurological disorders.
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1 mg$30In Stock
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Purity:98.72%
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Product Introduction

Bioactivity
Description
(S)-MCPG ((+)-MCPG) is a class I/II metabotropic glutamate receptors (mGluRs) antagonist that blocks spatial learning and long-term enhancement of the dentate gyrus in vivo in rats, and can be used to study neurological disorders.
In vivo
In male Lister-Hooded rats learning the Morris water maze, (S)-MCPG (20 μg; intraventricular injection; 4 days) impaired the performance of rats in the spatial version of the Morris water maze, but 1/10 of this dose did not[2].
Alias(+)-MCPG
Chemical Properties
Molecular Weight209.20
FormulaC10H11NO4
Cas No.150145-89-4
SmilesC[C@@](N)(C(O)=O)c1ccc(cc1)C(O)=O
Relative Density.1.390 g/cm3 (Predicted)
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 5 mg/mL (23.90 mM), Sonication is recommended.
H2O: 80 mg/mL (382.41 mM), Sonication and adjust pH to 13 with 1M OH
Solution Preparation Table
DMSO/H2O
1mg5mg10mg50mg
1 mM4.7801 mL23.9006 mL47.8011 mL239.0057 mL
5 mM0.9560 mL4.7801 mL9.5602 mL47.8011 mL
10 mM0.4780 mL2.3901 mL4.7801 mL23.9006 mL
20 mM0.2390 mL1.1950 mL2.3901 mL11.9503 mL
H2O
1mg5mg10mg50mg
50 mM0.0956 mL0.4780 mL0.9560 mL4.7801 mL
100 mM0.0478 mL0.2390 mL0.4780 mL2.3901 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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