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(Z)-PUGNAc, a potent O-GlcNAcase inhibitor more active than (E)-PUGNAc, removes O-GlcNAc from proteins (peptide O-GlcNAc-β-N-acetylaminoglucosidase) and can be used to increase levels of O-GlcNAc on nuclear and cytoplasmic proteins in vivo.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $66 | In Stock | |
5 mg | $158 | In Stock | |
10 mg | $293 | In Stock | |
25 mg | $497 | In Stock | |
50 mg | $726 | In Stock | |
100 mg | $980 | In Stock |
Description | (Z)-PUGNAc, a potent O-GlcNAcase inhibitor more active than (E)-PUGNAc, removes O-GlcNAc from proteins (peptide O-GlcNAc-β-N-acetylaminoglucosidase) and can be used to increase levels of O-GlcNAc on nuclear and cytoplasmic proteins in vivo. |
In vitro | In HeLa and HEK cell systems, (Z)-PugNAc amplifies the incorporation of O-GlcNAc onto proteins[1]. |
Molecular Weight | 353.33 |
Formula | C15H19N3O7 |
Cas No. | 132489-69-1 |
Smiles | CC(=O)NC1C(O)C(O)C(CO)OC1=NOC(=O)Nc1ccccc1 |
Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
Solubility Information | DMSO: 10 mg/mL (28.30 mM), Sonication is recommended. | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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