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α-Glucosidase

Catalog No. T41028 CAS 9001-42-7

Synonyms: α-D-Glucosidase

α-Glucosidase (α-D-Glucosidase) is a carbohydrate hydrolyzing enzyme that catalyzes the release of α-glucose from the non-reducing end of the substrate. It plays a vital role in facilitating glucose absorption by the small intestine. Inhibiting α-Glucosidase effectively manages non-insulin-dependent diabetes mellitus (NIDDM).

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α-Glucosidase, CAS 9001-42-7

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25 mg	Inquiry	$ 1,520.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description	α-Glucosidase (α-D-Glucosidase) is a carbohydrate hydrolyzing enzyme that catalyzes the release of α-glucose from the non-reducing end of the substrate. It plays a vital role in facilitating glucose absorption by the small intestine. Inhibiting α-Glucosidase effectively manages non-insulin-dependent diabetes mellitus (NIDDM).
In vivo	α-Glucosidase, a membrane-bound enzyme located in the small intestine's epithelium, facilitates glucose absorption by catalyzing the hydrolytic cleavage of oligosaccharides into absorbable forms. Inhibiting α-Glucosidase moderates postprandial blood sugar levels following carbohydrate ingestion[1].

Synonyms	α-D-Glucosidase
Molecular Weight	N/A
CAS No.	9001-42-7

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Kumar S, et, al. α-glucosidase inhibitors from plants: A natural approach to treat diabetes. Pharmacogn Rev. 2011 Jan;5(9):19-29. 2. Laar FA, et, al. Alpha-glucosidase inhibitors for patients with type 2 diabetes: results from a Cochrane systematic review and meta-analysis. Diabetes Care. 2005 Jan;28(1):154-63.

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

α-Glucosidase 9001-42-7 a-Glucosidase αGlucosidase α-D-Glucosidase α Glucosidase alpha-D-Glucosidase a-D-Glucosidase alpha-Glucosidase inhibitor inhibit

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