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Product Introduction

Bioactivity

Description	3-Methylcarbazole (NSC-10154) is an carbazole alkaloid compound with anticancer effects.
In vitro	3-Methylcarbazole shows growth inhibitory activity (IC50 of 25 μg/mL) on human fibrosarcoma HT-1080 cells[1].
Alias	NSC 10154

Chemical Properties

Molecular Weight	181.23
Formula	C₁₃H₁₁N
Cas No.	4630-20-0
Smiles	Cc1ccc2[nH]c3ccccc3c2c1

Storage & Solubility Information

Storage

Shipping with blue ice.

Solubility Information

DMSO: 90 mg/mL (496.6 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	5.5179 mL	27.5893 mL	55.1785 mL	275.8925 mL
5 mM	1.1036 mL	5.5179 mL	11.0357 mL	55.1785 mL
10 mM	0.5518 mL	2.7589 mL	5.5179 mL	27.5893 mL
20 mM	0.2759 mL	1.3795 mL	2.7589 mL	13.7946 mL
50 mM	0.1104 mL	0.5518 mL	1.1036 mL	5.5179 mL
100 mM	0.0552 mL	0.2759 mL	0.5518 mL	2.7589 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

NSC-10154NSC101543-Methylcarbazole