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3-Cyano-7-hydroxycoumarin

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Purity:98.03%

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COA HPLC HNMR

3-Cyano-7-hydroxycoumarin

Catalog No. T77674Cas No. 19088-73-4

3-Cyano-7-hydroxycoumarin (3-Cyanoumbelliferone) is a macrophage inhibitor of macrophage inhibitory factor (MIF) interconjugate isomerase with a Ki of 2.9 μM. 3-Cyano-7-hydroxycoumarin belongs to the group of coumarin derivatives, which can be used as molecular probes and fluorescent dyes.

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Pack Size	Price	Availability
10 mg	$30	In Stock
25 mg	$40	In Stock
50 mg	$64	In Stock
100 mg	$105	In Stock
500 mg	$344	In Stock

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Product Introduction

Bioactivity

Description	3-Cyano-7-hydroxycoumarin (3-Cyanoumbelliferone) is a macrophage inhibitor of macrophage inhibitory factor (MIF) interconjugate isomerase with a Ki of 2.9 μM. 3-Cyano-7-hydroxycoumarin belongs to the group of coumarin derivatives, which can be used as molecular probes and fluorescent dyes.
Alias	3-Cyanoumbelliferone

Chemical Properties

Molecular Weight	187.15
Formula	C10H5NO3
Cas No.	19088-73-4

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 15 mg/mL (80.15 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	5.3433 mL	26.7165 mL	53.4331 mL	267.1654 mL
5 mM	1.0687 mL	5.3433 mL	10.6866 mL	53.4331 mL
10 mM	0.5343 mL	2.6717 mL	5.3433 mL	26.7165 mL
20 mM	0.2672 mL	1.3358 mL	2.6717 mL	13.3583 mL
50 mM	0.1069 mL	0.5343 mL	1.0687 mL	5.3433 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

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A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

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Tech Support

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Keywords

3-Cyano-7-hydroxycoumarin